In the near future, Rhett Murphy and his estranged sister Jean are forced to flee from a militant police state after witnessing the dark secrets of a nefarious corporation.
Ana, an Oxford PhD student, finds herself unable to build new memories following an experiment to generate and travel through a wormhole.
It's the year 2150, the Earth is dying and its inhabitants are infected with a disease that causes terminal rage.
Adam receives a mysterious box from a relative containing a creature that will kill everyone he cares about. The only way to be rid of the curse is to give the box to someone he loves.